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Jean-Philip Truman Selected Research

spisulosine

1/20221-Deoxysphinganine initiates adaptive responses to serine and glycine starvation in cancer cells via proteolysis of sphingosine kinase.

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Jean-Philip Truman Research Topics

Disease

10Neoplasms (Cancer)
01/2022 - 01/2009
2Starvation
01/2022 - 01/2021
2Inflammation (Inflammations)
01/2018 - 03/2012
2Colonic Neoplasms (Colon Cancer)
12/2016 - 05/2014
2Fibrosarcoma
09/2010 - 01/2010
2Prostatic Neoplasms (Prostate Cancer)
01/2009 - 06/2005
2Ataxia Telangiectasia (Louis Bar Syndrome)
06/2005 - 05/2005
1Mitochondrial Diseases (Mitochondrial Disease)
01/2018
1Type 2F Charcot-Marie-Tooth disease
01/2018
1Neurodegenerative Diseases (Neurodegenerative Disease)
01/2018
1Major Depressive Disorder (Major Depressive Disorders)
03/2012
1Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder)
03/2012
1Vascular Diseases (Vascular Disease)
03/2012
1Systemic Lupus Erythematosus (Libman-Sacks Disease)
03/2012

Drug/Important Bio-Agent (IBA)

8SphingolipidsIBA
01/2021 - 06/2005
8CeramidesIBA
01/2020 - 06/2005
5EnzymesIBA
01/2021 - 06/2005
4sphingosine 1-phosphate (sphingosine-1-phosphate)IBA
01/2021 - 03/2012
3sphingosine kinaseIBA
01/2022 - 01/2018
3SphingosineIBA
01/2022 - 12/2016
3Sphingomyelin Phosphodiesterase (Sphingomyelinase)IBA
03/2012 - 01/2010
3AcidsIBA
03/2012 - 01/2010
3dihydroceramide desaturaseIBA
01/2009 - 05/2005
2Serine (L-Serine)FDA Link
01/2022 - 01/2021
2CateninsIBA
12/2016 - 05/2014
2AntibodiesIBA
09/2010 - 01/2010
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
09/2010 - 01/2010
2Phosphotransferases (Kinase)IBA
01/2009 - 05/2005
2Protein Kinase CIBA
01/2009 - 06/2005
2Ataxia Telangiectasia Mutated ProteinsIBA
01/2009 - 06/2005
1Biological ProductsIBA
01/2022
1TransferasesIBA
01/2022
1LipidsIBA
01/2022
1Alanine (L-Alanine)FDA Link
01/2022
1spisulosineIBA
01/2022
1Palmitoyl Coenzyme A (Palmitoyl CoA)IBA
01/2022
1Glycine (Aminoacetic Acid)FDA LinkGeneric
01/2022
1Pharmaceutical PreparationsIBA
01/2020
1HSP27 Heat-Shock ProteinsIBA
01/2018
1Neutral CeramidaseIBA
12/2016
1AzoxymethaneIBA
12/2016
1CytokinesIBA
03/2012
1Interleukin-10 (Interleukin 10)IBA
03/2012
1CholesterolIBA
03/2012
1InterferonsIBA
03/2012
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
03/2012
1Interleukin-6 (Interleukin 6)IBA
03/2012
1Nitric Oxide (Nitrogen Monoxide)FDA Link
03/2012
1Triglycerides (Triacylglycerol)IBA
03/2012
1Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
03/2012
1Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA
03/2012
1oxidized low density lipoproteinIBA
03/2012
1safingol (sphinganine)IBA
02/2009
1Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA
02/2009
1AndrogensIBA
01/2009
1LactonesIBA
01/2009
1DiglyceridesIBA
01/2009
1(1- (hydroxymethyl)- 4- (4- methyl- 3- (methylethyl)pentylidene)- 3- oxo- 2- oxolanyl)methyl 4-methyl-3-(methylethyl)pentanoateIBA
01/2009
1Proteins (Proteins, Gene)FDA Link
06/2005

Therapy/Procedure

5Therapeutics
12/2016 - 01/2009
2Radiotherapy
09/2010 - 01/2010